Ok..
Plugged the Dongle in, Drivers loaded, reboot for good measure. I run the USB Expert and it said there was an update. I applied the update.
However, I'm very sure I've driving the software correctly, but the 2 fixtures I'm using are not responding.
Running USB Expert, shows "Titan One Dmx Panel 1" with a "Chip Configuration Error" in the status pane:

Windows device manager reports no problems for the 2 Avolites devices.
I currently have 2 fixtures. 11 channel scanners.
They are correctly grouped.
I click ML Menu then Locate Fixtures.
I then click on the Group (so I guess this would control all/both fixtures).
I then click the "I" to allow me to adjust the Dimmer - nothing happens on the fixture.
I try the pan/tilt, again nothing happens on the fixture.
So, I'm currently stuck!
I guess, the "error" I see above - is that a problem? I can see another post regarding this, but it appears to not be a major issue for that member.
How can I tell if the software is using the DMX Dongle (as opposed to a simulator?). I can see the DMX settings under System, but its not clear what I should see (I can't see anything labeled as "Titan One DMX Panel 1"
Any help is greatful!
Cheers,
Jason